Friday, March 25, 2016

Dandelion root- another cancer killer herb

The University of Windsor Canada conveyed a study and the results gave new hope to cancer patients. It was found that the dandelion root effectively “kills” the cancer cells without harmful effects on the other healthy cells in the body.
John Di Carlo, 72 year-old man, was personally convinced in the healing properties of dandelion. After undergoing intense and “aggressive” chemotherapy for three years, the doctors sent him home to spend the last days with his loved ones.
Due to the fact that there was no positive effect of chemotherapy and doctors advised him to try alternative remedies to treat cancer, John began to drink tea from the dandelion root as a final attempt to defeat cancer. Only after four months, he defeated cancer for good.
Names:
Sanskrit:Simhadanti 

English: Dandelion 
Botanical:Taraxacum officinalis 
Hindi:Dudal, Kanphul 
Telugu:Simhadanti 
Common names: Blowball, cankerwort, lion's tooth, priest's crown, puffball, swine snout, white endive, wild endive, dandelion, Diente de leon, Pu gong ying 
Family name: Compositae 
2. Parts used:
  • Root
  • Leaves
Alkaloids: The chief constituents of Dandelion root are Taraxacin, acrystalline Vitamins A and C moderate amounts of vitamin D, vitamin C, various B vitamins, iron, silicon, magnesium, zinc, and manganese. The leaves are a rich source of potassiums.
3. Properties and Action According to Indigenous Medical Systems:
  • Rasa: Bitter.
  • Vipaka: Bitter.
4. Uses:
  • Good remedy for kidney and liver disorders.
  • Stimulates digestion.
  • It is a mild laxative, hepatic, aperient, diuretic, depurative, tonic and stomachic by nature.
  • Balances and bile production in the gallbladder and bile flow from the liver.
  • Supports liver function which is disturbed due to over alcoholism or poor diet.
  • It is blood purifier.
  • Induces metabolism in the body.
  • Good blood purifier hence also helps in the cases of eczema and cancer.
  • It relives constipation.
  • Enhances the formation of bile.
  • It removes excess water from body.
  • Removes toxins and poisons from the body.
  • It acts a good remedy for Jaundice because it increases the flow of urine in patients with liver problems.
  • It also cures skin diseases, scurvy, scrofula, and eczema.
  • Useful in all kinds of kidney troubles, diabetes, dropsy, inflammation of the bowels.
  • Good remedy for fever.
  • It induces production of mother's milk.
5. Names due to Physical properties:
  • Simhadanti: The leaves like teeth of lion.
  • Kanaka pushpi: Plant with yellow colored flowers.
  • Ksheera dari:The plant with milky sap.
6. Names due to Medical properties:
  • Vishamardhini: Detoxificant.
7. Reference:
Vasthu guna deepika, Vasthu guna prakashika, Chakradatta, Susrutam, Basabarajeezam, Bhavaprakashika, Vangacena, Charakasamhita, Vagvatamu, Hareetasamhita, Srijanakalpavalli.
8. Caution:
The milky sap of fresh Dandelion may cause allergy in some persons. The person, who has obstruction in bile ducts [like gallstones] has to take the Dandelion very carefully.

ayurveda recipes
Source: Healthy and Natural Life
 

Wednesday, March 2, 2016

Turmeric - a scientific confirmation OF MULTIFACTORIAL EFFECT IN DISEASE

Turmeric As Effective As 14 Drugs

Turmeric is one the most thoroughly researched plants in existence today.  Its medicinal properties and components (primarily curcumin) have been the subject of over 5600 peer-reviewed and published biomedical studies. 


Lipitor/Atorvastatin(cholesterol medication): A 2008 study published in the journal Drugs in R & D found that a standardized preparation of curcuminoids from Turmeric compared favorably to the drug atorvastatin (Lipitor) on endothelial dysfunction, the underlying pathology of the blood vessels that drives atherosclerosis, in association with reductions in inflammation and oxidative stress in type 2 diabetic patients.
Corticosteroids (steroid medications): A 1999 study published in the journal Phytotherapy Research found that the primary polyphenol in turmeric, the saffron colored pigment known as curcumin, compared favorably to steroids in the management of chronic anterior uveitis, an inflammatory eye disease.  A 2008 study published in Critical Care Medicine found that curcumin compared favorably to the corticosteroid drug dexamethasone in the animal model as an alternative therapy for protecting lung transplantation-associated injury by down-regulating inflammatory genes. An earlier 2003 study published in Cancer Letters found the same drug also compared favorably to dexamethasone in a lung ischaemia-repurfusion injury model.  [for additional
Prozac/Fluoxetine & Imipramine  (antidepressants): A 2011 study published in the journal Acta Poloniae Pharmaceutica found that curcumin compared favorably to both drugs in reducing depressive behavior in an animal model.
Aspirin (blood thinner): A 1986 in vitro and ex vivo study published in the journal Arzneimittelforschung found that curcumin has anti-platelet and prostacyclin modulating effects compared to aspirin, indicating it may have value in patients prone to vascular thrombosis and requiring anti-arthritis therapy
Anti-inflammatory Drugs: A 2004 study published in the journal Oncogene found that curcumin (as well as resveratrol) were effective alternatives to the drugs aspirin, ibuprofen, sulindac, phenylbutazone, naproxen, indomethacin, diclofenac, dexamethasone, celecoxib, and tamoxifen in exerting anti-inflammatory and anti-proliferative activity against tumor cells
  • Oxaliplatin (chemotherapy drug): A 2007 study published in the International Journal of Cancer found that curcumin compares favorably with oxaliplatin as an antiproliferative agenet in colorectal cell lines. [for additional curcumin and colorectal cancer research – 52 abstracts]
  • Metformin (diabetes drug): A 2009 study published in the journal Biochemitry and Biophysical Research Community explored how curcumin might be valuable in treating diabetes, finding that it activates AMPK (which increases glucose uptake) and suppresses gluconeogenic gene expression  (which suppresses glucose production in the liver) in hepatoma cells. Interestingly, they found curcumin to be 500 times to 100,000 times (in the form known as tetrahydrocurcuminoids(THC)) more potent than metformin in activating AMPK and its downstream target acetyl-CoA carboxylase (ACC).
  • -Curcumin clears >80% HPV-
    Asian Pac J Cancer Prev. 2013 ;14(10):5753-9. PMID: 24289574

    Abstract Author(s):
    Partha Basu, Sankhadeep Dutta, Rakiba Begum, Srabani Mittal, Paromita Das Dutta, Alok Chandra Bharti, Chinmay Kumar Panda, Jaydip Biswas, Bindu Dey, Gursaran Prashad Talwar, Bhudev Chandra Das
    Curcumin and curcumin containing polyherbal preparations have demonstrated anti-microbial and anti- viral properties in pre-clinical studies. Till date no therapeutic intervention has been proved to be effective and safe in clearing established cervical human papillomavirus (HPV) infection. The present study evaluated the efficacy of Basant polyherbal vaginal cream (containing extracts of curcumin, reetha, amla and aloe vera) and of curcumin vaginal capsules to eliminate HPV infection from cervix. Women were screened by Pap smear and HPV DNA test by PCR. HPV positive women without high grade cervical neoplasias (N=287) were randomized to four intervention arms to be treated with vaginal Basant cream, vaginal placebo cream, curcumin vaginal capsules and placebo vaginal capsules respectively. All subjects were instructed to use one application of the assigned formulation daily for 30 consecutive days except during menstruation and recalled within seven days of the last application for repeat HPV test, cytology and colposcopy. HPV clearance rate in Basant arm (87.7%) was significantly higher than the combined placebo arms (73.3%). Curcumin caused higher rate of clearance (81.3%) than placebo though the difference was not statistically significant. Vaginal irritation and itching, mostly mild to moderate, was significantly higher after Basant application. No serious adverse events were noted.
  • Click here to read the complete article.
  • Ulcerative Colitis and Crohn's disease- Effect of Turmeric is researched for these diseases and it seems help.Link to article.
  • READ MORE AT HERE.
  • Apricot seeds and Peach Seeds reduces tumor activity


    Abstract Title:
    Anti-tumor promoting effect of glycosides from Prunus persica seeds.

    Abstract Source:
    Biol Pharm Bull. 2003 Feb;26(2):271-3. PMID: 12576693

    Abstract Author(s):
    Toshiyuki Fukuda, Hideyuki Ito, Teruo Mukainaka, Harukuni Tokuda, Hoyoku Nishino, Takashi Yoshida
    Abstract:
    Four minor components, along with the major cyanogenic glycosides, amygdalin and prunasin, were isolated from Prunus persica seeds (Persicae Semen; Tounin), and characterized as mandelic acid glycosides (beta-gentiobioside and beta-D-glucoside) and benzyl alcohol glycosides (beta-gentiobioside and beta-D-glucoside). The anti-tumor promoting activity of these compounds was examined in both in vitro and in vivo assays. All of the compounds significantly inhibited the Epstein-Barr virus early antigen activation induced by tumor promoter. In addition, they produced a delay of two-stage carcinogenesis on mouse skin that was comparable in potency to (-)-epigallocatechin gallate from green tea. Structure-activity relationships indicated that a substituent at the benzylic position with glycosidic linkage affected the in vitro and in vivo activities with an order of enhancing potency, CN<COOH<H.


    Apricot seeds, kills Leukemia cells


    Abstract Title:
    Apoptosis induction of Persicae Semen extract in human promyelocytic leukemia (HL-60) cells.

    Abstract Source:
    Arch Pharm Res. 2003 Feb;26(2):157-61. PMID: 12643594

    Abstract Author(s):
    Hee-Young Kwon, Seon-Pyo Hong, Dong-Hoon Hahn, Jeong Hee Kim
    Abstract:
    The major ingredient of Persicae Semen is a cynogenic compound, amygdalin (D-mandelonitrile-beta-gentiobioside). Controversial results on the anticancer activity of amygdalin were reported due to its conversion to its inactive isomer, neoamygdalin. In order to inhibit the epimerization of amygdalin, we used newly developed simple acid boiling method in preparation of Persicae Semen extract. HPLC analysis revealed most of amygdalin in Persicae Semen extract was active D-form. Persicae Semen extract was used to analyze its effect on cell proliferation and induction of apoptosis in human promyelocytic leukemia (HL-60) cells. Persicae Semen extract was cytotoxic to HL-60 cells with IC50 of 6.4 mg/mL in the presence of 250 nM of beta-glucosidase. The antiproliferative effects of Persicae Semen extract appear to be attributable to its induction of apoptotic cell death, as Persicae Semen extract induced nuclear morphology changes and internucleosomal DNA fragmentation.


    Study Type : In Vitro Study

    MIRACLE ANTI CANCER EFFECTS OF Bitter Almond (Apricot Kernels)-A reality hiding

    Apricot Kernels and Bitter Almonds
    There has been numerous amazing :got rid of cancer" or "cancer free"  after taking or consuming bitter almonds everyday. In natural history of man, nature provided many ways to heal and get rid of waste products but food industry blinded people and many physicians in past and some now ignite that fire towards food processing company like- eat meat everyday, protein can only be received from meat, eggs, animal origin , and food industry made animals a just eating material. Was that supposed to be .No Animals are before humans and they have equal right to live but let me not to go there , and be limited to this post's heading.
    The apricot pits contain a compound called glycosides which are a combination of sugar and cyanide called "Amygdalin" have been used successfully around the world for the reversal of many types of cancer. The Hunza tribes in the Himalayans are virtually cancer free, because of their daily consumption of apricot pits and millet, both of which contain amygdalin.

    What takes place here is what we call selective toxicity. Cancer cells needs sugar to survive and grow. A specific enzyme that is produced in large quantities by cancer cells, triggers the sugar break down that releases the cyanide. The cyanide is what kills the cancer cells.

    Healthycells not affected by the cyanide because of enzyme called rhodanese, which makes the cyanide harmless. How's that for another amazing healing miracle?
    Amygdalin also inhibits angiogenesis, which is  the formation of new blood flow as the cancer cells to grow. Hampering blood flow to the tumor is makes cancer cells die.

    Amygdalin also suppresses inflammatory responses which lead to multiple diseases, including cancer.

    Specific studies have shown how amygdalin induces apoptosis or cell death in prostate cancer cells, human colon cancer cells and in leukemia cells.

    Amygdalin even inhibits the growth of the Epstein-Barr virus, which often induces tumor growth. The anti-tumor promoting activity of amygdalin and other compounds was studied in both in vitro and in vivo assays.

    While administered specifically for cancer treatment, a wonderful side effect is that amygdalin actually helps relieve the pain that is often associated with aggressive cancers.




    While administered specifically for cancer treatment, a wonderful side effect is that amygdalin actually helps relieve the pain that is often associated with aggressive cancers.
    Laetrile is synthetic form of Amygdalin but natural is better.


    Dr. Veronique Desaulniers MD


    Research about colon cancer


    Read full article









    Bitter Almoind- a miracle to help cure Prostate Cancer.



    Abstract Title:
    Amygdalin induces apoptosis through regulation of Bax and Bcl-2 expressions in human DU145 and LNCaP prostate cancer cells.

    Abstract Source:
    Biol Pharm Bull. 2006 Aug;29(8):1597-602. PMID: 16880611

    Abstract Author(s):
    Hyun-Kyung Chang, Mal-Soon Shin, Hye-Young Yang, Jin-Woo Lee, Young-Sick Kim, Myoung-Hwa Lee, Jullia Kim, Khae-Hawn Kim, Chang-Ju Kim
    Abstract:
    Prostate cancer is one of the most common non-skin cancers in men. Amygdalin is one of the nitrilosides, natural cyanide-containing substances abundant in the seeds of plants of the prunasin family that have been used to treat cancers and relieve pain. In particular, D-amygdalin (D-mandelonitrile-beta-D-gentiobioside) is known to exhibit selective killing effect on cancer cells. Apoptosis, programmed cell death, is an important mechanism in cancer treatment. In the present study, we prepared the aqueous extract of the amygdalin from Armeniacae semen and investigated whether this extract induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells. In the present results, DU145 and LNCaP cells treated with amygdalin exhibited several morphological characteristics of apoptosis. Treatment with amygdalin increased expression of Bax, a pro-apoptotic protein, decreased expression of Bcl-2, an anti-apoptotic protein, and increased caspase-3 enzyme activity in DU145 and LNCaP prostate cancer cells. Here, we have shown that amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax. The present study reveals that amygdalin may offer a valuable option for the treatment of prostate cancers.


    Study Type : Animal Study

    Amygdalin in Bitter almond could inhibit colon cancer growth


    Abstract Title:
    Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cells
    Abstract Source:
    World J Gastroenterol. 2005 Sep 7;11(33):5156-61. PMID: 16127745



    Abstract Author(s):
    Hae-Jeong Park, Seo-Hyun Yoon, Long-Shan Han, Long-Tai Zheng, Kyung-Hee Jung, Yoon-Kyung Uhm, Je-Hyun Lee, Ji-Seon Jeong, Woo-Sang Joo, Sung-Vin Yim, Joo-Ho Chung, Seon-Pyo Hong


    Abstract:
    AIM: The genes were divided into seven categories according to biological function; apoptosis-related, immune response-related, signal transduction-related, cell cycle-related, cell growth-related, stress response-related and transcription-related genes. METHODS: We compared the gene expression profiles of SNU-C4 cells between amygdalin-treated (5 mg/mL, 24 h) and non-treated groups using cDNA microarray analysis. We selected genes downregulated in cDNA microarray and investigated mRNA levels of the genes by RT-PCR. RESULTS: Microarray showed that amygdalin downregulated especially genes belonging to cell cycle category: exonuclease 1 (EXO1), ATP-binding cassette, sub-family F, member 2 (ABCF2), MRE11 meiotic recombination 11 homolog A (MRE11A), topoisomerase (DNA) I (TOP1), and FK506 binding protein 12-rapamycin-associated protein 1 (FRAP1). RT-PCR analysis revealed that mRNA levels of these genes were also decreased by amygdalin treatment in SNU-C4 human colon cancer cells. CONCLUSION: These results suggest that amygdalin have an anticancer effect via downregulation of cell cycle-related genes in SNU-C4 human colon cancer cells, and might be used for therapeutic anticancer drug.



    Study Type : In Vitro Study


    Other study are also favoring for many natural ingredients that could inhibit cancer groth-

    See comment in PubMed Commons below
    2009 Jul;27(6):604-12. doi: 10.1080/07357900802337191.

    Quercetin inhibit human SW480 colon cancer growth in association with inhibition of cyclin D1 and survivin expression through Wnt/beta-catenin signaling pathway.

    CONCLUSION:

    The results indicate that the molecular mechanism underlying the antitumor effect of quercetin in SW480 colon cancer cells is related to the inhibition of expression of cyclin D(1) and survivin as well as the Wnt/beta-catenin signaling pathway. Therefore, the Wnt/beta-catenin signaling pathway could be qualified as one of the promising targets for innovative treatment strategies of colorectal cancer.




    Bitter almonds and bladder cancer
    NIH research
    Anti cancer Quercetin